CAR(T) cell therpy

Chimeric antigen receptor (CAT) T-cell therapy is a way to get immune cells called T cells (a type of white blood cell) to fight cancer by changing them in the lab so they can find and destroy the cancer cells.

CAT-T cell therapy is also sometimes talked about as a type of cell-based gene therapy because it involves altering genes inside T cells to help them attack the cancer.

Thus, immune system recognizes foreign substance in the body by finding protein called antigens on the surface of those cells.

Immune cells called T cells have their own protein called receptors that attacks the foreign antigen and help trigger other parts of the immune system to destroy the foreign substances.

In CAR-T cell therapy T cells taken from the patient’s blood and are changed in the lab by adding a gene for a receptor (called CAR) which helps the T cells to attach to the specific cancer cell antigen. The CAT-T cells are given back to the patient.


  1. T cell (collect blood) _______ 2. Isolation and reprogramming of T cells

                                                                      (CART cell) 

  • Multiplication ___________    Injection _____ 5. CART cell attack cancer cell
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